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Organic compounds that contain two carboxyl groups; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from dicarboxylic acids.
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Small-molecule allosteric activator of glutathione peroxidase 4 (GPX4) used as a research tool to study ferroptosis and inflammation. Reported activity includes an approximate pEC50 of 4.7 and an ability to increase GPX4 activity in biochemical assays. Supplied as a solid with good solubility in DMSO for assay preparation.
Allosteric activation of glutathione peroxidase 4 with reported pEC50 ≈ 4.7.
Shown to increase GPX4 activity to about 150% in biochemical assays.
Useful for probing ferroptosis and inflammation pathways in preclinical research.
Supplied as a solid with high DMSO solubility for convenient dilution and assay use.
Vendor-reported molecular formula and molecular weight provided for analytical reference.
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Chemical. CAS 82354-19-6. Formula C31H29ClN2O6S2. MW 625.15. Synthetic. Sulforhodamine 101 sulfonyl chloride also called Texas Red sulfonyl chloride is a popular long wavelength amine-reactive rhodamine dye. Because the dye is quite unstable in water, reactions with amines in an aqueous solution must be carried out at low temperature over ice or at 4°C and usually at pH 8.5.
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Lauroyl-L-carnitine chloride is an acylcarnitine-derived absorption enhancer used in research to increase the oral bioavailability of peptide compounds. It is provided as a high-purity solid for laboratory use and can be prepared as solutions for experimental assays following recommended storage conditions.
Orally active absorption enhancer for peptide compounds.
Improves oral bioavailability of peptide therapeutics in preclinical studies.
Supplied as a high-purity solid suitable for solution preparation.
Available in small research pack sizes and larger quantities on request.
Stable when stored sealed at 4°C; in solution store at -80°C (6 months) or -20°C (1 month).
Molecular formula C19H38ClNO4; molecular weight 379.96 g·mol⁻¹.
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CUDC-101 is a small-molecule research inhibitor of histone deacetylases (HDACs), epidermal growth factor receptor (EGFR), and HER2, used in preclinical cancer research to assess antiproliferative and target-specific effects.
Potent inhibitor of HDAC, EGFR, and HER2 with low-nanomolar activity.
Demonstrates broad antiproliferative effects across cancer cell lines.
Supplied as a light yellow to yellow powder for laboratory use.
High purity suitable for research applications (reported ≥98% by HPLC).
Available in small-mass packaging for research workflows.
Molecular weight 434.49 g/mol.
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MAL3-101 is a small-molecule allosteric inhibitor of heat shock protein 70 (HSP70) used in cellular and biochemical research. It inhibits HSP70 ATPase activity by blocking interaction with Hsp40 co-chaperones, perturbing protein folding and proteostasis pathways. The compound is supplied as a high-purity research reagent (CAS 831217-40-4) and is intended for in vitro and preclinical studies only.
Allosteric inhibitor of HSP70 ATPase activity.
Blocks Hsp40-Hsp70 interaction to disrupt protein folding.
Applicable to cellular models studying proteostasis and cancer biology.
High reported purity supports reproducible results.
Supplied in small quantities suitable for screening and pilot studies.
For research use only; not for human or veterinary use.
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1 2-Dilauroyl-sn-glycerol (CAS No 60562-15-4) is a synthetic diacylglycerol analog commonly used in biochemical and cellular research to study signal transduction pathways Originating from the glycerolipid family it acts as an activator of protein kinase C (PKC) a key component in various signaling cascades PKC is implicated in cellular processes such as differentiation proliferation and apoptosis This compound exhibits in vitro activity in the nanomolar to low micromolar range facilitating studies on its effects at the molecular level It is often applied in cell models including cultured mammalian cells to investigate cellular responses and in animal studies for its potential therapeutic implications Its consistency in behavior makes it valuable for screening drug candidates targeting PKC pathways Experimental concentrations typically depend on the specific research design allowing for optimization based on the targeted outcomes and biological systems employed
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Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins. purity: 98%
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Sodium lauroyl glutamate is an anionic amino acid surfactant used primarily in cleaning products. It is considered a mild surfactant with low irritation to nude mouse skin, exhibiting a pH value of 5.41. It also has potential for irritant contact dermatitis and possible anti-irritating effects in surfactant mixtures on human skin.
Anionic amino acid surfactant
Mild surfactant properties
Ideal for cleaning product formulations
Low irritation potential
pH value of 5.41
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Lauroyl-L-carnitine chloride is an orally active metabolite. It significantly reverses the decrease in its target gene IL-10 and alleviates Crohn's-like colitis. This compound exhibits anti-inflammatory effects and improves both systemic and local phenotypes in TNBS mice.
Orally active metabolite
Significantly reverses decrease in IL-10
Alleviates Crohn's-like colitis
Exhibits anti-inflammatory effects
Improves systemic and local phenotypes in TNBS mice
For research use only
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BNC-101 is a human-derived antibody expressed in CHO cells that targets GPR49/LGR5 The predicted molecular weight (MW) of BNC-101 is 150 kDa The isotype control for BNC-101 can refer to Human IgG1 kappa Isotype Control (HY-P99001)
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GlyH-101 is a research-grade small-molecule inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR). It is used in cellular and electrophysiological studies to block CFTR-mediated chloride conductance and has reported antiproliferative activity. Supplied as a purified, characterized compound for laboratory research.
Potent CFTR inhibitor for cellular and electrophysiology assays.
Reversible blockade of VSORC conductance.
High purity (99.7%).
Molecular weight 493.15 g/mol.
Molecular formula C19H15Br2N3O3.
Supplied as a 10 mg vial for research use.
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BNC-101 is a human-derived antibody expressed in CHO cells that targets GPR49/LGR5 The predicted molecular weight (MW) of BNC-101 is 150 kDa The isotype control for BNC-101 can refer to Human IgG1 kappa Isotype Control (HY-P99001)
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More