Dicarboxylic acids and derivatives
Medchemexpress LLC 1,2-Dilauroyl-sn-glycerol | 60562-15-4 | 98.0% | 100 MG
1,2-Dilauroyl-sn-glycerol is identified as a saturated diacylglycerol that might be involved in second messenger signal transduction. It is available as a solid, appearing white to off-white, with a molecular weight of 456.70 and the chemical formula C27H52O5. This compound is intended strictly for research purposes.
- Saturated diacylglycerol.
- May play a role in second messenger signal transduction.
- Available in solid form.
- Appears white to off-white.
- Strictly for research use.
- High purity of 98.0%.
Selleck Chemical LLC CUDC-101 S1194-10mM/1mL
CUDC-101 is a potent multi-targeted inhibitor against HDAC EGFR and HER2 with IC50 of 4 4 nM 2 4 nM and 15 7 nM and inhibits class I/II HDACs but not class III Sir-type HDACs Phase 1
Selleck Chemical LLC Sulforhodamine 101-E0366-5MG
Sulforhodamine 101 (SR101) is a fluorescent dye and is widely used for astrocyte identification
Selleck Chemical LLC PHI-101-E1437-100MG
PHI-101 is an orally active potent third-generation inhibitor of FLT3 that overcomes resistance to multiple drug-resistant mutations It has potential for research in relapsed or refractory acute myeloid leukemia (AML)
![Medchemexpress LLC N-(2-(1H-indol-3-yl)ethyl)-5-(5-fluoropyridin-3-yl)-3-methylpyrazolo[1,5-a]pyrimidin-7-amine | 2247950-73-6 | 98.0% | C22H19FN6 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261386.png-250.jpg)
Medchemexpress LLC N-(2-(1H-indol-3-yl)ethyl)-5-(5-fluoropyridin-3-yl)-3-methylpyrazolo[1,5-a]pyrimidin-7-amine | 2247950-73-6 | 98.0% | C22H19FN6 | 10MG
KYN-101 is a small-molecule, selective, orally active antagonist of the aryl hydrocarbon receptor (AHR) supplied for laboratory research. It reduces CYP1A1 mRNA expression and has demonstrated anti-cancer activity in preclinical studies, making it suitable for mechanistic studies of AHR signaling and oncology research.
- Selective AHR inhibition with reported nanomolar potency.
- Orally active in preclinical models.
- Reduces CYP1A1 mRNA expression in cellular assays.
- Useful for mechanistic studies of AHR signaling and cancer biology.
- Available as solid and ready-to-use DMSO solutions for assay setup.
- High purity suitable for research applications.
![Medchemexpress LLC 1-propanaminium, 3-carboxy-N,N,N-tri(methyl-d3)-2-[(1-oxododecyl)oxy]-, chloride (1:1), (2R)- | 2245711-25-3 | 98.0% | C19H29D9ClNO4 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000260025.png-250.jpg)
Medchemexpress LLC 1-propanaminium, 3-carboxy-N,N,N-tri(methyl-d3)-2-[(1-oxododecyl)oxy]-, chloride (1:1), (2R)- | 2245711-25-3 | 98.0% | C19H29D9ClNO4 | 10MG
Lauroyl-L-carnitine-d9 chloride is the deuterium-labeled (d9) chloride salt of lauroyl-L-carnitine supplied as an isotope-labeled reference standard for analytical and research use. It is intended for use as an internal standard or tracer in mass spectrometry, quantitative assays, and metabolic or pharmacokinetic studies, providing a labeled analog of the unlabeled compound.
- Deuterium-labeled (d9) isotope suitable for use as an internal standard in mass spectrometry.
- Chloride salt form to match common analytical reference materials.
- High purity (98.0%) for reliable analytical performance.
- Provided in small, reference quantities tailored for analytical workflows.
- Stable when stored sealed under refrigerated conditions (≈2-8°C).
Medchemexpress LLC Lauroyl-L-carnitine-d9 chloride | 2245711-25-3 | MFCD34676545 | 98.0% | 389.02 g/mol | C19H29D9ClNO4 | 5 MG
Lauroyl-L-carnitine-d9 chloride is the deuterium-labeled chloride salt of lauroyl-L-carnitine supplied for analytical and tracer applications. It is intended for use as a stable-isotope internal standard in bioanalytical, pharmacokinetic, and tracer studies where mass spectrometry differentiation is required.
- Stable isotope labeled internal standard for mass spectrometry
- Deuterated (d9) for clear mass separation from native compound
- High purity (98.0%) suitable for analytical workflows
- Chloride salt form for compatibility with common assays
- Supplied in a 5 mg quantity for small-scale analyses
Medchemexpress LLC Lauroyl-L-carnitine chloride | 6919-91-1 | 98.1% | 1 ML
Lauroyl-L-carnitine chloride is an orally active metabolite that significantly reverses the decrease in its target gene IL-10 and alleviates Crohn's-like colitis. This product is for research use only.
- Orally active metabolite
- Reverses decrease in IL-10
- Alleviates Crohn's-like colitis
- Exhibits anti-inflammatory effects
- Improves systemic and local phenotypes of TNBS mice
Medchemexpress LLC Lauroyl-L-carnitine (chloride) | 6919-91-1 | 98.1% | 1 MG
Lauroyl-L-carnitine chloride is an orally active metabolite that significantly reverses the decrease in its target gene IL-10, alleviating Crohn's-like colitis. It demonstrates anti-inflammatory effects and improves both systemic and local phenotypes in TNBS mice.
- Orally active metabolite
- Reverses decrease in target gene IL-10
- Alleviates Crohn's-like colitis
- Exhibits anti-inflammatory effects
- Improves systemic and local phenotypes in TNBS mice
Medchemexpress LLC 1,2-Dilauroyl-sn-glycerol | 60562-15-4 | 98.0% | 50 MG
1,2-Dilauroyl-sn-glycerol is a saturated diacylglycerol that may be involved in second messenger signal transduction. It appears as a white to off-white solid with a molecular formula of C27H52O5 and a molecular weight of 456.70. This product is intended for research use only.
- Purity of 98.0%
- CAS number: 60562-15-4
- Soluble in DMSO (100 mg/mL), requiring ultrasonic for dissolution
- Ships at room temperature within the continental US
- Recommended storage for powder: -20°C for 3 years
- Recommended storage for in-solvent solutions: -80°C for 6 months, or -20°C for 1 month (aliquot and store to prevent inactivation from repeated freeze-thaw cycles)
- Related to metabolic enzymes/proteases and endogenous metabolites
- Acts as an inhibitor
TARGETMOL CHEMICALS INC GLYH-101 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM. purity: 98%
Medchemexpress LLC 1,2-Dilauroyl-sn-glycerol | 60562-15-4 | 98.0% | 25 MG
1,2-Dilauroyl-sn-glycerol is a saturated diacylglycerol that may participate in second messenger signal transduction. It is intended for research use only and is not sold to patients.
- Potential role in second messenger signal transduction.
- Crucial intracellular signaling molecules involved in regulating various physiological processes.
- Specifically designated for research purposes.
Medchemexpress LLC VH 101, acid | 2408341-97-7 | 98.8% | 574.66 | C28H35FN4O6S | 10 MG
VH 101, acid is a functionalized von Hippel-Lindau (VHL) E3 ligase ligand developed for PROTAC research and conjugation chemistry. The molecule includes an E3 ligase recognition motif and an alkyl linker terminating in a primary amine, facilitating attachment to target protein ligands.
- Designed for use as a VHL E3 ligase ligand in PROTAC development.
- Alkyl linker with terminal amine enables straightforward conjugation chemistry.
- High reported purity suitable for research applications.
- Supplied in small research-scale quantities for synthetic work and assay testing.
Medchemexpress LLC 4H-1-Benzopyran-3-carbonitrile, 2-amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(1-naphthalenyl) | 1118460-77-7 | 98.61% | 422.48 | 100 MG
UCPH-101 is a potent excitatory amino acid transporter subtype 1 (EAAT1) inhibitor, demonstrating an IC50 of 0.66 μM. This compound is intended for research applications only and is not suitable for patient use.
- Inhibits EAAT1 anion currents with a KD value of 0.34±0.03 μM (Hill=1.3±0.13, n≥9).
- Causes a small but significant decrease in total expression levels of HA-EAAT1 and HA-GLAST in cells preincubated with 100 μM UCPH-101 (p=0.048).
Medchemexpress LLC UCPH-101 | 1118460-77-7 | 98.6% | 422.48 | 10 MG
UCPH-101 is an excitatory amino acid transporter subtype 1 (EAAT1) inhibitor with an IC50 of 0.66 μM. It functions as an allosteric modulator, inducing sustained inhibition of EAAT1 through an intramonomeric site within the trimerization domain. In vitro studies show that UCPH-101 inhibits EAAT1 anion currents in a concentration-dependent manner, with a KD value of 0.34±0.03 μM. This compound is intended for research use only.
- Inhibits excitatory amino acid transporter subtype 1 (EAAT1)
- Functions as an allosteric modulator
- Demonstrates sustained inhibition of EAAT1 anion currents
- IC50 of 0.66 μM
- KD value of 0.34±0.03 μM for EAAT1 anion currents