Dicarboxylic acids and derivatives
Apexbio Technology LLC GlyH-101 328541-79-3 10mg
GlyH-101 (CAS 328541-79-3) is a cell-permeable glycinyl hydrazone derivative that acts as a selective inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel exhibiting a Ki of 1 4 M By blocking CFTR-mediated chloride transport GlyH-101 serves as a valuable tool for investigating CFTR function in epithelial physiology and pathophysiology as well as for studying mechanisms underlying cystic fibrosis and related disorders involving chloride ion dysregulation
Medchemexpress LLC 1,2-dilauroyl-sn-glycero-3-phosphoethanolamine | 59752-57-7 | MFCD00042828 | 98.0% | 579.75 g·mol⁻¹ | C29H58NO8P | 100 MG
1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE) is a phosphatidylethanolamine derivative bearing two lauroyl (C12:0) acyl chains. It is a research-grade lipid commonly used for liposome formulation and membrane model studies; typical properties include a molecular weight of 579.75 g·mol⁻¹ and high purity (98.0%).
- Phosphatidylethanolamine lipid with two lauroyl (C12:0) chains.
- Suitable for liposome synthesis and membrane model studies.
- High purity (98.0%) for research applications.
- Molecular formula C29H58NO8P and molecular weight 579.75 g·mol⁻¹.
Medchemexpress LLC Pigment Yellow 101 | 2387-03-3 | 98.1% | 5 MG
Pigment Yellow 101 is a yellow bis-azomethine pigment with excitation/emission at 411 nm/512 nm. It exhibits solid-state fluorescence and is available as a commercial colorant. This product is for research use only and not sold to patients.
- Yellow bis-azomethine pigment
- Exhibits solid-state fluorescence
- Excitation/emission: 411 nm/512 nm
- Available as a commercial colorant
TARGETMOL CHEMICALS INC PKUMDL-LC-101-D04 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4) a regulator of iron death. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 uM in a cell-free assay and at a concentration of 61 uM in wild-type but not Gpx4-/- mouse embryonic fibroblast (MEF) extracts.PKUMDL-LC-101-D04 (200 uM) reduced cholesterol peroxide-induced MEF death. purity: 98%
Medchemexpress LLC Lauroyl-L-carnitine chloride | 6919-91-1 | MFCD00274131 | 98.1% | C19H38ClNO4 | 10MG
Lauroyl-L-carnitine chloride is an orally active absorption enhancer used in research to improve the oral bioavailability of peptide compounds. Supplied as a white to off-white solid with high purity, it is applied in formulation and permeability studies to assess and enhance intestinal uptake of peptide drugs.
- Orally active absorption enhancer for peptide compounds.
- Reported to improve oral bioavailability of peptides.
- White to off-white solid suitable for formulation research.
- High purity (~98.1%) as supplied.
- Supports studies of intestinal permeability and delivery.
- Store sealed at 4°C; in solvent, -80°C (6 months) or -20°C (1 month).
![Medchemexpress LLC O=C([C@]1(CO1)CO[Si](C)(C)C(C)(C)C)[C@H](CC(C)C)NC([C@H](C)NC(CCCCCC)=O)=O | 1000313-40-5 | 99.6% | 484.74 | C25H48N2O5Si | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000229462.png-250.jpg)
Medchemexpress LLC O=C([C@]1(CO1)CO[Si](C)(C)C(C)(C)C)[C@H](CC(C)C)NC([C@H](C)NC(CCCCCC)=O)=O | 1000313-40-5 | 99.6% | 484.74 | C25H48N2O5Si | 5 MG
UK-101 is a selective immunoproteasome β1i (LMP2) inhibitor for laboratory research. It shows reported potency with an IC50 of about 104 nM and is supplied as a high-purity solid suitable for in vitro studies; recommended solvent is DMSO.
- Selective immunoproteasome β1i (LMP2) inhibitor with IC50 ≈104 nM.
- High purity (≈99.6%).
- Available in small research quantities, e.g., 5 mg.
- Recommended solvent: DMSO for dissolution.
- Powder storage: -20°C (3 years) or 4°C (2 years); solutions: -80°C (6 months).
- For research use only; not for human or clinical use.
Medchemexpress LLC Phenylmethyl ester | 831217-40-4 | UPCMLD00WMAL3-101 | 98.2% | 931.12 g/mol | C54H66N4O10 | 25MG
MAL3-101 is a small-molecule allosteric inhibitor of HSP70 used in biochemical and cellular research to modulate HSP70 ATPase activity and disrupt Hsp40 co-chaperone interactions. It is a membrane-permeable dihydropyrimidine analog supplied as a solid powder for laboratory use.
- Allosteric inhibitor of HSP70 ATPase activity.
- Disrupts Hsp40 co-chaperone interaction.
- Demonstrated activity in cellular antiproliferative studies.
- High purity suitable for research (>98%).
- Powder form with DMSO solubility for assay preparation.
- Recommended storage: powder at -20°C; in solvent at -80°C for longer storage.
Selleck Chemical LLC CUDC-101 S1194-10mM/1mL
CUDC-101 is a potent multi-targeted inhibitor against HDAC EGFR and HER2 with IC50 of 4 4 nM 2 4 nM and 15 7 nM and inhibits class I/II HDACs but not class III Sir-type HDACs Phase 1
Medchemexpress LLC Lauroyl-L-carnitine chloride | 6919-91-1 | 98.1% | 1 ML
Lauroyl-L-carnitine chloride is an orally active metabolite that significantly reverses the decrease in its target gene IL-10 and alleviates Crohn's-like colitis. This product is for research use only.
- Orally active metabolite
- Reverses decrease in IL-10
- Alleviates Crohn's-like colitis
- Exhibits anti-inflammatory effects
- Improves systemic and local phenotypes of TNBS mice
Medchemexpress LLC Lauroyl-L-carnitine (chloride) | 6919-91-1 | 98.1% | 1 MG
Lauroyl-L-carnitine chloride is an orally active metabolite that significantly reverses the decrease in its target gene IL-10, alleviating Crohn's-like colitis. It demonstrates anti-inflammatory effects and improves both systemic and local phenotypes in TNBS mice.
- Orally active metabolite
- Reverses decrease in target gene IL-10
- Alleviates Crohn's-like colitis
- Exhibits anti-inflammatory effects
- Improves systemic and local phenotypes in TNBS mice
Medchemexpress LLC Lauroyl-L-carnitine (chloride) | 6919-91-1 | 98.1% | 25 MG
Lauroyl-L-carnitine chloride is an orally active metabolite. It significantly reverses the decrease in its target gene IL-10 and alleviates Crohn's-like colitis.
- Orally active metabolite
- Reverses decrease in IL-10 gene
- Alleviates Crohn's-like colitis
- Purity: 98.14%
Medchemexpress LLC Sodium lauroyl glutamate | 29923-31-7 | 95.8% | 5 G
Sodium lauroyl glutamate is an anionic amino acid surfactant with potential for irritant contact dermatitis and possible anti-irritating potential in surfactant mixtures on human skin.
- Anionic amino acid surfactant
- Potential for irritant contact dermatitis
- Possible anti-irritating potential
Medchemexpress LLC 1,2-Dilauroyl-sn-glycerol | 60562-15-4 | 98.0% | 25 MG
1,2-Dilauroyl-sn-glycerol is a saturated diacylglycerol that may participate in second messenger signal transduction. It is intended for research use only and is not sold to patients.
- Potential role in second messenger signal transduction.
- Crucial intracellular signaling molecules involved in regulating various physiological processes.
- Specifically designated for research purposes.
TARGETMOL CHEMICALS INC AVN-101 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AVN-101 is a very potent 5-HT7 receptor antagonist (Ki = 153 pM). AVN-101 also exhibits a rather high affinity toward histamine H1 (Ki = 0.58 nM) and adrenergic (alpha)2A (alpha)2B and (alpha)2C (Ki = 0.41-3.6 nM) receptors. AVN-101 shows a good oral bioavailability and facilitated brain-blood barrier permeability low toxicity and reasonable efficacy in animal models of CNS diseases. purity: 99%
Selleck Chemical LLC GlyH-101
GlyH-101 is a selective and reversible CFTR inhibitor with Ki of 4 3 M